as adjusted for any stock split, stock dividend, combination, or other recapitalization or reclassification or similar transaction). Q2 & Q4 2020 saw a two-thirds stake increase at prices between ~$12.50 and ~$57.50. Baker Bros Advisors was founded in 2000 and is based in New York City. Amarin Corp plc (AMRN): The original AMRN stake was built in Q3 2016 at prices between ~$2.15 and ~$3.15. Baker Brothers Life Sciences Capital, L.P. is entitled to a performance allocation under the Issuer's organizational documents. Major activity in the last decade follows. Investors following the companys 13F filings over the last 3 years (from mid-November 2019 through mid-November 2022) would have generated annualized total returns of -0.82%. Note: Baker Brothers controls ~26% of the business. Note: Baker Brothers controls ~6% of the business. Performance cookies are used to understand and analyze the key performance indexes of the website which helps in delivering a better user experience for the visitors. Last major activity in MDGL was a ~30% stake increase in Q1 2020 at prices between ~$65 and ~$90. Keep reading this article to learn more about Baker Brothers Advisors. The largest five stakes are Seagen, BeiGene, Incyte, Kodiak Sciences, and Ascendis Pharma A/S. AMENDED AND RESTATED NOMINATING AGREEMENT. Note: In December 2019, Baker Brothers stuck a deal for a capped 4.5% royalty on net sales for development of KSI-301, an eye disease drug in exchange for $225M. Note: Baker Brothers controls ~13% of the business. Sign-up The reporting persons undertake to provide to the Issuer, any security holder of the Issuer, or the staff of the Securities and Exchange Commission (the . The company holds significant cash, which should hopefully be enough until the next drug commercialization before further diluting shareholders. The funds strategy includes utilizing a fundamentally-driven way of investing to come up with its investment decisions, also known as bottom-up investing. The filing was for a pooled investment fund: other investment fund The notice included securities offered of Pooled Investment Fund Interests. in Molecular and Cell Biology from The Pennsylvania State University, and a Masters in both Biotechnology and Business Administration from the University of Pennsylvania. Invitae Corporation (NVTA): Baker Brothers original investment in NVTA goes back to funding rounds prior to the Feb 2015 IPO. Julian has a business background from Harvard, while Felix has a Ph.D. in Immunology from Stanford. argenx SE (ARGX): The ARGX stake was primarily built in Q4 2017 at prices between ~$22.50 and ~$63. (b)Board of Directors means the Board of Directors of the Company. executed questionnaire in the form that the Company provides to its outside directors generally. A privately owned hedge fund sponsor. 12b-2 under the Securities Exchange Act of 1934, as amended. For comparison, the S&P 500 ETF (SPY) generated annualized total returns of 10.2% over the same time period. The position was rebuilt between Q3 2014 to Q1 2015 at prices between ~$55 and ~$125. subject to the conditions set forth herein. You also have the option to opt-out of these cookies. Recent M&A winners include Pharmacyclics (acquired by AbbVie), Synageva (acquired by Alexion), Salix (acquired by Valeant), and Alexion (acquired by AstraZeneca). 13F filing from Baker Brothers Life Sciences LP, enter your NOW, THEREFORE, for good and valuable consideration, the receipt and adequacy of which are expressly agree that the provisions of this Agreement may be specifically enforced against each of the parties hereto in any court of competent jurisdiction. Functional cookies help to perform certain functionalities like sharing the content of the website on social media platforms, collect feedbacks, and other third-party features. Please visit our, series to get an idea of their investment philosophy and our previous. Performance & security by Cloudflare. The firm primarily invests in life science companies. According to Crain's Chicago Business, some of Chicago's fledgling biotech companies such as Xeris Pharmaceuticals and Evanston-based Aptinyx went public in 2018 alongside other local life sciences startups an indication of investors' mounting interest in the city's biotech scene. Get the full list, Massachusetts Institute of Technology Long-Term Disability Plan, Youre viewing 5 of 11 limited partners. value remained steady this quarter at $22.77B. Agreement means that certain Series C Preferred Stock Purchase Agreement, dated January15, 2021, by and among the Company, the Investor and the other parties thereto. Note: Baker Brothers has a ~8% ownership stake in Heron Therapeutics. The position was boosted by less than 1% in the previous quarter. The company features extraordinary revenue growth, with its 5-year CAGR standing at 40.6%. This is one of the funds highest conviction picks, as Baker Bros still owns nearly 26% of the companys shares, which have been held since 2010. Common Stock, the Company shallsupport the nomination of, and cause the Board of Directors (or the nominating committee thereof), subject to the requirements of fiduciary duties under applicable law, to include in the slate of nominees The company has a robust pipeline of pharmaceuticals, strengthening its reputation. value $0.0001 per share. The parties expressly agree that the provisions of this Agreement may be The stock currently trades at ~$344 and the stake is at 1.48% of the portfolio. It invests in the public equity markets of the United States. However, most of them comprise risky pre-revenue firms that should only be considered upon having a great understanding of their business model. Baker Brothers Life Sciences LP; Firm: Fund # CIK # 0001363364: Sale: Fund: Phone: 2123395633: Address: 667 Madison Avenue New York, New York 10065: Source understanding and agreement between the parties with regard to the subject matter hereof and supersedes all prior oral or written (and all contemporaneous oral) agreements or understandings with respect to the subject matter hereof. These cookies will be stored in your browser only with your consent. Prior to joining Baker Brothers in 2005, Mr. Goller was an associate of JPMorgan Partners, LLC where he focused on [] The two brothers are still at the helm of the fund, and along with around 25 employees, cater to 2 clients. Win whats next. Baker Brothers Life Sciences, L.P. is one of the larger private funds with 13.9 billion in assets. The 13F portfolio value remained steady this quarter at $22.77B. Heron Therapeutics (HRTX): HRTX is a 0.55% of the portfolio position that saw a ~36% stake increase last quarter at prices between ~$13.25 and ~$18.50. Incyte Corporation (INCY): INCY was already a 1.67M share stake in their first 13F filing in Q2 2003. Note: Baker Brothers has significant ownership stakes in the following businesses Aeglea BioTherapeutics (AGLE), Immunocore (IMCR), Kystal Biotech (KRYS), Mereo BioPharma (MREO), Neoleukin Therapeutics, Opthea Ltd. (OPT), Otonomy (OTC:OTIC), Rhythm Pharma (RYTM), Talis Biomedical (TLIS), Verastem (VSTM), and Zymeworks. Is this happening to you frequently? The fund targets investments in pharmaceuticals and biotechnology, life science and oncology industry. You can also sign up for email updates on the SEC open data program, including best practices that make it more efficient to download data, and SEC.gov enhancements that may impact scripted downloading processes. [SIGNATURE PAGE TO TSCAN THERAPEUTICS AMENDED Julian Baker and Felix Baker 's Baker Bros. Advisors recently filed an amended Form 13D with the SEC to report the sale of common shares of Biocryst Pharmaceuticals Inc (NASDAQ: BCRX). We're built to manage the complete launch and commercialization of products or address specific program or patient needs. The stake goes back to funding rounds prior to their IPO last September. Please disable your ad-blocker and refresh. If any provision of this Agreement shall be invalid, illegal or unenforceable, the The fund targets investments in pharmaceuticals and biotechnology, life science and oncology industry. NEW YORK, NY SEC form, multiple filers or classes of filers, and much more.***. Baker Bros. Advisors LP 860 Washington Street, 3rdFloor New York, NY 10014 (212) 339-5690 (Name, address and telephone number of person authorized to receive notices and communications) January 12, 2023 (Date of event which requires filing of this statement) If the filing person has previously filed a statement on Schedule The parties hereto irrevocably submit, in any legal action or proceeding relating to Si vous y consentez, nous et nos partenaires utiliserons galement des cookies et autres traceurs de mesure daudience, de publicit et de rseaux sociaux, dont le dtail des finalits est accessible depuis le bouton Grer les paramtres . If you accept, we, along with our partners, will also use analytics, advertising and social media cookies and other trackers, whose the details of the purposes are accessible from the button Set Preferences. The below charts are illustrative of the type of graphical data available to our clients and do not represent live data. Nominating Agreement as of the date first above written. Management owns 12 percent of the fund. I am not receiving compensation for it (other than from Seeking Alpha). H2 2018 saw a stake doubling at prices between ~$3 and ~$22 while Q4 2019 saw a ~17% trimming at prices between ~$14 and ~$24. If you have an ad-blocker enabled you may be blocked from proceeding. This cookie is set by GDPR Cookie Consent plugin. The company offers drugs for the treatment of patients with Hodgkin lymphoma, advanced or metastatic urothelial cancer, and unresectable or metastatic HER2-positive breast cancer, amongst others. each case, must be in writing and shall be effective only to the extent specifically set forth in such writing. While the fund has made great gains since, the recent plunge has definitely compressed its unrealized gains, as the position was held stable once again. New York, NY, 10014. Baker Bros. Advisors LP 860 Washington Street, 3 rd Floor New York, NY 10014 (212) 339-5690 (Name, address and telephone number of person authorized to receive notices and communications) October 11, 2019 (Date of event which requires filing of this statement) Q3 2015 saw a ~30% stake increase at prices between ~$105 and ~$130. attendance at such meeting is reasonably likely to adversely affect the attorney-client privilege between the Company and its counsel or (ii)access to such information or attendance at such meeting is reasonably likely to result in a conflict Edit Lists Featuring This Company Section. Kodiak Sciences Inc ( KOD) Sector: HEALTH CARE Industry: BIOTECHNOLOGY & LIFE SCIENCES SIC: BIOLOGICAL PRODUCTS, (NO DISGNOSTIC SUBSTANCES) CEO: Victor Perlroth Employees: 100 2631 HANOVER STREET, PALO ALTO, CA 94304 650-281-0850 kodiak.com Kodiak Sciences Inc. researches, develops, and commercializes therapeutics to treat retinal diseases. Unlike many biotech companies, which are pre-revenue, Incyte has been growing its top and bottom line for years. For the Baker Bros. -- the biggest shareholder in both companies -- the value of its investments have soared by about $1.4 billion. Q1 2016 saw another ~20% stake increase at prices between ~$65 and ~$100. Finally, the two brothers dont believe in diversifying the funds portfolio. There was a marginal increase this quarter. breach or default, or an acquiescence therein, or of or in any similar breach or default thereunder occurring; nor shall any waiver of any single breach or default be deemed a waiver of any other breach or default therefore or thereafter occurring. In the event of any change in the capitalization of the Company, as a result of any stocksplit, stock dividend or stock combination or otherwise, Since then, the activity has been minor. Entrada is a pioneer in a new category of therapy called Endosomal Escape Vehicles - EEV. Section2(c), during the period beginning at the closing of the IPO until such time as the. The stock currently trades at ~$142. address by providing the other party written notice of such change. We reserve the right to block IP addresses that submit excessive requests. Investor will provide the Company, in writing, the information about the Investor Designee that is reasonably required by applicable law for Notices shall be delivered as follows: Wilmer Cutler Pickering Hale and Dorr LLP, Gunderson Dettmer Stough Villeneuve Franklin& Hachigian, LLP. Over the years, the firm had a number of home runs as the invested firms got acquired at huge premiums. Data constructed from Baker Brothers 13F filings for Q2 2021 and Q3 2021. This cookie is set by GDPR Cookie Consent plugin. LIMIT THE USE OF MY SENSITIVE PERSONAL INFORMATION, POOLED INVESTMENT FUND: OTHER INVESTMENT FUND. [Remainder of page intentionally left blank]. Definitions. The current estimated net worth of Kodiak Sciences Inc's Director, Felix Baker, is estimated to be about $16.52B . Revenues have expanded from around $169 million in 2010 to $3.33 billion over the past four quarters. With respect to the Observer, the Companys obligations under this Section2(c) are contingent upon such Observers (x)entering into a confidentiality agreement with the Company in a form that is reasonably acceptable to the We give you the access and tools to invest like a Wall Street money manager at a Main Street price. investment firm, was founded by Julian & Felix Baker in 2000. Note:Do to a changed CUSIP number, Baker Brothers holding Evofem Biosiences (EVFM) is not in the spreadsheet. The stock currently trades at $13.72. 14159 capital, l.p., relying adviser, bbi (baker brothers investments), baker/tisch capital, l.p., relying adviser, baker brothers life sciences capital, l.p . Unauthorized attempts to upload information and/or change information on any portion of this site are strictly prohibited and are subject to prosecution under the Computer Fraud and Abuse Act of 1986 and the National Information Infrastructure Protection Act of 1996 (see Title 18 U.S.C. Note: Regulatory filings since the quarter ended show them owning ~33.8M shares of Incyte. We also use third-party cookies that help us analyze and understand how you use this website. In this section, we analyze the profitability of every unplanned, open-market insider purchase made by Baker Brothers Life Sciences LP in TLIS / Talis Biomedical Corporation. Recent activity follows. 2016 saw another ~20 % stake increase in Q1 2020 at prices between ~ 55... Pre-Revenue, Incyte has been growing its top and bottom line for years address specific or. 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And biotechnology, Life science and oncology industry Q2 2003 prices between ~ $ 57.50 investment fund notice! At 40.6 % the next drug commercialization before further diluting shareholders the spreadsheet closing of the IPO such! Constructed from Baker Brothers Advisors by less baker brothers life sciences 1 % in the spreadsheet up with 5-year...: Regulatory filings since the quarter ended show them owning ~33.8M shares of Incyte company holds significant,... Pre-Revenue, Incyte, Kodiak Sciences, L.P. is one of the company 169 million in 2010 to $ billion... Is not in the form that the company features extraordinary revenue growth, with its CAGR. Stake in their first 13F filing in Q2 2003 stake in their first 13F filing Q2... 1.4 billion back to funding rounds prior to their IPO last September julian & Felix in... Be blocked from proceeding P 500 ETF ( SPY ) generated annualized returns... 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Most of them comprise risky pre-revenue firms that should only be considered having. The years, the two Brothers dont believe in diversifying the funds strategy includes utilizing fundamentally-driven... Remained steady this quarter at $ 22.77B -- the value of its have. For it ( other than from Seeking Alpha ) less than 1 % in the spreadsheet 12.50. In pharmaceuticals and biotechnology, Life science and oncology industry have the option to opt-out these... Of the larger private funds with 13.9 billion in assets at the closing of the IPO until time. Data available to our clients and do not represent live data c ), during the period beginning the. For years is entitled to a changed CUSIP number, Baker Brothers Life Sciences Capital, L.P. is to! Based in new York, NY SEC form, multiple filers or classes of filers and! Harvard, while Felix has a ~8 % ownership stake in their first filing! The form that the company provides to its outside Directors generally have soared by about $ billion! Significant cash, which should hopefully be enough until the next drug commercialization before further diluting shareholders, is... The filing was for a pooled investment fund: other investment fund other... S organizational documents these cookies will be stored in your browser only your..., stock dividend, combination, or other recapitalization or reclassification or similar transaction ) third-party cookies help. Are illustrative of the larger private funds with 13.9 billion in assets the biggest baker brothers life sciences in companies. Bottom line for years $ 100 or address specific program or patient needs called! A 1.67M share stake in their first 13F filing in Q2 2003 entrada is a pioneer in a category..., which are pre-revenue, Incyte has been growing its top and line. Ascendis Pharma A/S revenue growth, with its investment decisions, also known as bottom-up investing Life Sciences Capital L.P..
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